Manual de Direito do Trabalho
Xavier, Bernardo da Gama Lobo
2011-01-01
Search results
16 records were found.
The regioselective N-alkylation of 1,2,3-triazoles 1 - 6 was studied. Good to excellent N-2 selectivity and high chemical yields for N-2-substituted 4,5-dibromotriazoles 7 were obtained with 4,5-dibromo- and 4-bromo-5- trimethylsilyl-1,2,3-triazoles. These building blocks can be readily converted to 2-mono-, 2,4-di-, and 2,4,5-polysubstituted triazoles 10 - 15, providing a general, protective, group-free method for the synthesis of N-2-substituted triazoles. Observed regioselectivities can be rationalized by a combination of Frontier Molecular Orbital, steric, and electrostatic directing effects on the heterocyclic scaffolds. © 2010 American Chemical Society.
Abstract
Introduction
Pathologists currently diagnose breast lesions through histologic assessment, which requires fixation and tissue preparation. The diagnostic criteria used to classify breast lesions are qualitative and subjective, and inter-observer discordance has been shown to be a significant challenge in the diagnosis of selected breast lesions, particularly for borderline proliferative lesions. Thus, there is an opportunity to develop tools to rapidly visualize and quantitatively interpret breast tissue morphology for a variety of clinical applications.
Methods
Toward this end, we acquired images of freshly excised breast tissue specimens from a total of 34 patients using confocal fluorescence microscopy and proflavine...
Introduction: Pathologists currently diagnose breast lesions through histologic assessment, which requires fixation and tissue preparation. The diagnostic criteria used to classify breast lesions are qualitative and subjective, and inter-observer discordance has been shown to be a significant challenge in the diagnosis of selected breast lesions, particularly for borderline proliferative lesions. Thus, there is an opportunity to develop tools to rapidly visualize and quantitatively interpret breast tissue morphology for a variety of clinical applications. Methods: Toward this end, we acquired images of freshly excised breast tissue specimens from a total of 34 patients using confocal fluorescence microscopy and proflavine as a topical stain. We developed computerized algorithms to segment and quantify nuclear and ductal parameters that...
Abstract
Introduction
Pathologists currently diagnose breast lesions through histologic assessment, which requires fixation and tissue preparation. The diagnostic criteria used to classify breast lesions are qualitative and subjective, and inter-observer discordance has been shown to be a significant challenge in the diagnosis of selected breast lesions, particularly for borderline proliferative lesions. Thus, there is an opportunity to develop tools to rapidly visualize and quantitatively interpret breast tissue morphology for a variety of clinical applications.
Methods
Toward this end, we acquired images of freshly excised breast tissue specimens from a total of 34 patients using confocal fluorescence microscopy and proflavine...
Bosques y silvicultura, Desarrollo urbano, Gestión de recursos naturales, Desarrollo proyectos de áreas verdes urbanas
We present a measurement of the time-dependent CP-violating asymmetries in neutral B decays to the $\pi^+\pi^-$ CP eigenstate, and an updated measurement of the charge asymmetry in $B^0\to K^+\pi^-$ decays. In a sample of 33 million $\Upsilon(4S)\to B\bar B$ decays collected with the BABAR detector at the SLAC PEP-II asymmetric $B$ Factory, we find $65^{+12}_{-11}$ $\pi^+\pi^-$ and $217\pm 18$ $K^+\pi^-$ candidates and measure the asymmetry parameters $S_{\pi\pi} = 0.03^{+0.53}_{-0.56}\pm 0.11$, $C_{\pi\pi} = -0.25^{+0.45}_{-0.47}\pm 0.14$, and ${\cal A}_{K\pi} = -0.07 \pm 0.08 \pm 0.02$, where the first error is statistical and the second is systematic.
The production of $J/\psi$ mesons in continuum $e^+e^-$ annihilations has been studied with the BABAR detector at energies near the $\Upsilon(4S)$ resonance, approximately 10.6 GeV. The mesons are distinguished from $J/\psi$ production in B decays through their center-of-mass momentum and energy. We measure the cross section $e^+e^-\to J/\psi X$ to be $2.52\pm 0.21\pm 0.21$ pb; for momentum above 2 GeV/c, it is $1.87\pm 0.10\pm 0.15$ pb. We set a 90% confidence level upper limit on the branching fraction for direct $\Upsilon(4S)$\to J/\psi X$ decays at $4.3\times 10^{-4}$.
We have observed the decays B-->phi K and phi K^* in a sample of over 45 million B mesons collected with the BABAR detector at the PEP-II collider. The measured branching fractions are BF(B^+ --> phi K^+) = (7.7^{+1.6}_{-1.4}+/- 0.8) x 10^{-6}, BF(B^0 --> phi K^0) = (8.1^{+3.1}_{-2.5}+/- 0.8) x 10^{-6}, BF(B^+ --> phi K^{*+}) = (9.7^{+4.2}_{-3.4}+/- 1.7) x 10^{-6} and BF(B^0 --> phi K^{*0}) = (8.6^{+2.8}_{-2.4}+/- 1.1) x 10^{-6}. We also report the upper limit BF(B^+ --> phi pi^+) 1.4 x 10^{-6}$ (90% CL).
We report branching fraction measurements for exclusive decays of charged and neutral B mesons into two-body final states containing a charmonium meson. We use a sample of 22.72 +/- 0.36 million B anti-B events collected between October 1999 and October 2000 with the BABAR detector at the PEP-II storage rings at the Stanford Linear Accelerator Center. The charmonium mesons considered here are J/psi, psi(2S), and chi_c1, and the light meson in We report branching fraction measurements for exclusive decays of charged and neutral B mesons into two-body final states containing a charmonium meson. We use a sample of 22.72 +/- 0.36 million B anti-B events collected between October 1999 and October 2000 with the BABAR detector at the PEP-II storage rings at the Stanford Linear Accelerator Center. The charmonium mesons considered here are J/ps...
