Commentary on Section 264 of ITAA 1936: commissioner may require information and evidence
Dabner, Justin
2007-01-01
Search results
6 records were found.
A monoclonal antibody against the surface
marker IOT-10 of natural killer (NK) cells was used to
investigate the presence of these cells in a series of twenty
intracranial meningiomas. In al1 of these tumours, IOT-
10 positive NK cells were found in small numbers, mainly
distributed among the tumor cells. Two recurrent tumors
showed a relatively high number of immunostained cells.
The data obtained in the present study suggest that a NKcell-
mediated immunological response can occur in
meningioma tissue.
The presence of IOT-10-positive lymphocytes
among the tumor-infiltrating-lymphocyte (TIL)
population was studied in a series of 185 brain tumors.
In most of the tumors, IOT-10-positive lymphocytes
were identified, but generally they were scarce and
masked among the tumor cells, suggesting that NK-cells
exercise a poor participation in the tissular response
against brain tumors. Isolated tumor cells showing IOT-
10-positivity were found in low-grade astrocytomas,
neurinomas and medulloblastomas. IOT- 10-positivity on
both tumor neuropil and tumor cells was considered a
characteristic finding in oligodendrogliomas. The
number of IOT- 10-positive NK-cells in brain metastases
and in cerebellar hemangioblastomas was comparatively
greater than in other types of brain tumor. Since in brain
metastases, the presence of IOT-10-pos...
We present the irnmunohistochernical study
of 11 cases of intracranial cysts: two extraventricular
ependymal cysts, three colloid cysts of the third
ventricle, four extraventricular choroidal cysts and two
Rathke's cleft cysts. Antibodies against glial fibrillary
acidic protein (GFAP), cytokeratins (AE1, CKSD, AE3),
S-100 protein, epithelial membrane antigen (EMA),
vimentin, neuron specific enolase (NSE), neurofilaments
protein (NF) and prealbumin, were used. The epithelium
of choroidal cysts, showed strong immunoreactivity for
Prealbumin and cytokeratins, similar to the normal
choroid plexus epithelium. The ependymal cysts showed
epithelial immunoreactivity for GFAP and S-100, both
glial markers expressed by the normal ependymal
epithelium. On the contrary, the epithelial wall of colloid
cysts and Rathke's cleft cyst, e...
A series of 18 tumors with histological
features of oligodendrogliomas, induced in the rat by
means of transplacental ethyl-nitrosurea administration
were studied for immunohistochemical demonstration of
neuronal (synaptophysin and neurofilament protein) and
glial (gliofibrillar acidic protein and vimentin) markers.
Most of the tumors showed cells with strong positivity to
synaptophysin and to a lesser degree, to neurofilament
protein, suggesting the neuronal character of these
neoplasms. In 10 tumors, cells with strong positivity to
vimentin were found, and in three cases, tumoral cells
expressed gliofibrillar acidic protein. The observation
that ENU-induced oligodendroglial tumors express
neuronal and, to a minor degree, glial markers, suggests
their interpretation as prirnitive neuroectodermal tumors
with clear neuron...
Four ethyl-nitrosourea (ENU)-induced
oligodendroglioma-like tumors of the rat showing large
rosettes on haematoxylin-eosin stain were studied by
means of immunohistochemistry and electron
microscopy, and their features compared with six human
intraventricular neurocytomas. The similarities between
the experimental and human tumors studied support the
hypothesis that most of the so-called ENU-induced
oligodendrogliomas in the rat are primitive
neuroectodermal tumors with the tendency to
differentiate toward a neuronal phenotype, and also
suggest that the ENU-model of neurocarcinogenesis is
useful for the induction of experimental neurocytomas.
Assembly of paramagnetic Cu2 complexes with a Schiff base scaffold possessing extended electron delocalization together with a quasi-planar structure onto carbon nanotubes induces a diameter-selective charge transfer from the complex to the nanotubes leading to an interestingly large and tunable ambipolar effect. We used complementary techniques such as electron paramagnetic resonance, absorption spectroscopy, and photoluminescence to ensure the success of the assembly process and the integrity of the complex in the nanohybrid. We carried out density functional theory type calculations to rationalize the experimental results,evidencing the selective enhanced interaction of the metal complexes with one type of nanotube.
